Peptid-Synthese im MultiPep: Capturing the interaction between histones and their deacetylases with hydroxamic acid-modified microarrays
4. Feb. 2021 | Ulf Sengutta
Histone deacetylases (HDACs) modify the epigenetic code recorded on histones. This landscape of modifications can be altered with drugs, such as HDAC inhibitors, to silence genes involved in cancer progression. Studying the HDAC‒histone interaction may help elucidate these mechanisms.