Web-Seminar „Schnelle und innovative Mikrowellen-Aufschlussmethoden für Umweltproben und Lebensmittel / Bedarfsgegenstände“

Für die Lebensmittel- und Bedarfsgegenstände-Analytik (§ 64 LFGB) und die Umweltanalytik sind schnelle, leistungsfähige und innovative Aufschlussverfahren von entscheidender Bedeutung. Das Aufschlussverfahren muss auf die nachfolgende Analytik der Hydrid-/Kaltdampf-/Flammen- oder Graphitofen-AAS, ICP-OES bzw. ICP-MS abgestimmt sein. Im Rahmen dieses Web-Seminars erläutern Ihnen die Referenten Frank Scholten und Ulf Sengutta die modernen Mikrowellen-Aufschlussmethoden von wenigen Milligramm […]

Online Seminar: Latest Developments in Peptide Synthesis

10. März 2021, ab 10.15 Uhr Erleben Sie einen ganzen Tag interessante Vorträge zu den Neuigkeiten der Peptid-Synthese. Aufgrund der Corona-Situation können Präsenzvorträge derzeit nicht stattfinden. Deshalb veranstaltet CEM zusammen mit bekannten Forschern/innen dieses kostenfreie Online Seminar. Academic Guest Speakers: Professor Anna Maria Papini University of Florence, CY Cergy Paris Université The challenge to design […]

IRBM and Sanofi publish in J. Med. Chem. on optimizing the Relaxin-2 peptide hormone in cardiovascular disease

Peptid-Synthese im Liberty Blue The insulin-like peptide human relaxin-2 was identified as a hormone that, among other biological functions, mediates the hemodynamic changes occurring during pregnancy. Recombinant relaxin-2 (serelaxin) has shown beneficial effects in acute heart failure, but its full therapeutic potential has been hampered by its short half-life and the need for intravenous administration […]

Lösemittelfreie Mikrowellen-Synthese: Direct amidation of carboxylic acids with amines under microwave irradiation using silica gel as a solid support

A highly improved and green methodology for the direct amidation of carboxylic acids with amines using silica gel as a solid support and catalyst is described. The scope of this method is exemplified by the use of several aliphatic, aromatic, unsaturated and fatty acids. The reaction is also applied to different primary and secondary amines. […]

Web-Seminar zur Extraktion von Umweltschadstoffen

Mittwoch, 24.2.2021 um 14.00 Uhr Soil is one of the most common matrices in which semi-volatile organic compounds (SVOCs) are present. The extraction of these compounds from soil can be a lengthy and tedious process. Pressurized Fluid Extraction on the EDGE and Microwave Assisted Solvent Extraction (MASE) on the MARS 6 are proven techniques that […]

Warum eigentlich Mikrowellen-Synthese?

Mikrowellenunterstützte Synthesen ermöglichen den Synthese-Chemikern ganz neue Wege zum gewünschten Produkt (Wirkstoff). Mit einem Höchstmaß an Flexibilität und bisher nicht vorhandenen Kontrollmöglichkeiten der Reaktionsparameter ermöglicht die Mikrowellen-Chemie ein direktes Einkoppeln der Energie in die gewünschten Reaktionen. In kürzester Zeit wird die notwendige Aktivierungsenergie der Reaktion zugeführt, was sich in der Beschleunigung gegenüber traditionellen Reaktionsbedingungen niederschlägt. […]

The Use of Microwave Radiation in Preparation of the Carbonaceous Adsorbents

Justyna KAŹMIERCZAK-RAŹNA, Piotr NOWICKI, Robert PIETRZAK Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii Pracownia Chemii Stosowanej ul. Umultowska 89b, 61-614 Poznań The Use of Microwave Radiation in Preparation of the Carbonaceous Adsorbents Activated carbons from low quality hay were obtained with the use of microwave heat-ing and applied as adsorbents of gaseous pollutants of […]

An Optimized Scalable Fully Automated Solid-Phase Microwave-Assisted cGMP-Ready Process for the Preparation of Eptifibatide

The authors investigated several strategies, based on the use of microwave-assisted solid-phase peptide synthesis (MW-SPPS) and scalable to kilogram-scale manufacturing, for the preparation of Eptifibatide, a disulfide-bridged cyclo-heptapeptide drug approved as an antithrombotic agent. Following the very fast microwave-assisted Fmoc/tBu synthesis of the linear precursor, we explored both the solution (off-resin) and the solid-phase (on-resin) […]

Microwave chemistry for inorganic nanomaterials synthesis

This Feature Article gives an overview of microwave-assisted liquid phase routes to inorganic nanomaterials. Whereas microwave chemistry is a well-established technique in organic synthesis, its use in inorganic nanomaterials‘ synthesis is still at the beginning and far away from having reached its full potential. However, the rapidly growing number of publications in this field suggests […]